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Soothe occasional digestive distress

Gut feelings can help prevent sticky situations, but some gut feelings are rather less desirable, such as heartburn, gas, bloating, constipation, and diarrhea. Most of us have experienced gastrointestinal discomfort at some point, with digestive health easily upset by the stresses and strains of modern life, as well as dietary choices and some medications.

GastroAssist™ from Natural Factors offers comprehensive gastrointestinal support thanks to mastic gum, two probiotic strains, chamomile, and zinc/L-carnosine chelate. This unique formula is designed to offer relief from occasional digestive discomfort, help address symptoms of inflammatory conditions of the gastrointestinal tract, and promote gastric healing while reducing the risk of antibiotic-associated diarrhea.

Heartburn Support from Mastic Gum
Each non-GMO, vegetarian-friendly capsule of GastroAssist contains 130 mg of mastic gum, a type of resin long been prized in herbal medicine for the relief of heartburn and abdominal discomfort resulting from indigestion. Mastic gum can soothe symptoms of indigestion and stomach and intestinal ulcers and guard against bacterial and fungal infections.

In one randomized, placebo-controlled trial, 77% of people with dyspepsia who took mastic gum for 3 weeks had improvements in symptoms including stomach pain, upper abdominal ache, stomach pain when anxious, and heartburn (1).

Soothing Chamomile
Chamomile is one of the oldest medicinal plants and is well known for its soothing qualities. The effects of this herb are likely related to its ability to influence smooth muscle tone in the gut, resulting in antidiarrheal, anti-secretory, and antispasmodic activity (2).

Chamomile has long been used to address gastrointestinal disorders, stomach ache, and other ailments (2). Like mastic gum, chamomile may also enhance antioxidant status, helping to protect the stomach and intestines from oxidative damage (3).

GastroAssist features 100 mg of chamomile to help soothe occasional digestive complaints.

Probiotics – A natural way to support digestion
Intestinal bacterial balance can be upset by many factors, including stress, diet, infection, and antibiotics. GastroAssist features two probiotics to help support microflora balance: Saccharomyces boulardii and BB536® Bifidobacterium longum.

BB536® is a proprietary room-temperature stable strain of B. longum. This probiotic helps to increase levels of beneficial gut bacteria, support normal immune function, and guard against digestive problems. BB536® has been shown to provide a natural defense against several pathogens associated with diarrhea (4). It may also reduce production of inflammatory cytokines and immunoglobulin-E, helping to protect mucous membranes and support healthy immune function (5).

Saccharomyces boulardii is one of the best studied probiotics for acute gastroenteritis and is a recommended probiotic for the prevention of antibiotic-associated diarrhea (AAD) (7). Traditionally used in Europe to treat diarrhea and support immune function, S. boulardii may support conventional treatment for Helicobacter pylori eradication, including helping to reduce side effects of treatment (6). In one clinical trial, people taking S. boulardii during antibiotic treatment for H. pylori eradiation had just a 5.9% incidence of diarrhea, compared with an 11.5% incidence in a placebo group (7).

Zinc for Digestive and Immune Support
Zinc is an essential mineral needed for hundreds of enzymatic reactions. It plays a role in healing and immunity, growth and reproductive health, metabolism, and digestive enzyme production. Zinc/L-carnosine can help maintain a healthy mucosal lining and support bacterial balance in the digestive system.

As part of the zinc/L-carnosine complex, zinc is released slowly in the stomach, offering a longer window in which the mineral can enhance gastric healing. This may help address issues such as increased gut permeability associated with some medications such as the non-steroidal anti-inflammatory drugs (NSAIDs) indomethacin and aspirin (8, 9).

GastroAssist features 18.75 mg of zinc with L-carnosine in every capsule to support normal gastric healing and natural immunity.

GastroAssist from Natural Factors is an excellent option for anyone looking to support digestive health in general and promote better immune function, especially for anyone with inflammation-related gastrointestinal issues. Anyone taking antibiotics should take GastroAssist at least 2-3 hours before or after such medications.

Two capsules a day can help relieve occasional digestive discomfort, such as in cases of heartburn, constipation, diarrhea, bloating, gas and indigestion, while helping to protect tissues in the stomach and intestines and promote normal healing processes. GastroAssist helps support digestion so you can get back to trusting those gut feelings.

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References
1. Dabos, K.J., et al. Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. (2010). J Ethnopharmacol. 127(2), 205-209.
2. Mehmood, M.H., et al. (2015). Antidiarrhoeal, antisecretory and antispasmodic activities of Matricaria chamomilla are mediated predominantly through K+-channels activation. BMC Complement Altern Med. 15(1), 75.
3. Kolodziejczyk-Czepas, J., et al. (2015). Radical scavenging and antioxidant effects of Matricaria chamomilla polyphenolic-polysaccharide conjugates. Int J Biol Macromol. 72, 1152-8.
4. Ishizeki, S., et al. Effect of administration of bifidobacteria on intestinal microbiota in low-birth-weight infants and transition of administered bifidobacteria: a comparison between one-species and three-species administration. (2013). Anaerobe. 23, 38-44.
5. Xiao, J.Z., et al. Probiotics in the treatment of Japanese cedar pollinosis: a double-blind placebo-controlled trial. (2006). Clin Exp Allergy. 36(11), 1425-35.
6. Dinleyici, E.C., et al. Saccharomyces boulardii CNCM I-745 in different clinical conditions. (2014) Expert Opin Biol Ther. 14(11), 1593-609.
7. Duman, D.G., et al. Efficacy and safety of Saccharomyces boulardii in prevention of antibiotic-associated diarrhoea due to Helicobacterpylori eradication. (2005). Eur J Gastroenterol Hepatol. 17(12), 1357-61.
8. Mahmood, A., et al. Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes. (2007). Gut. 56(2), 168-75.
9. Watari, I., et al. Effectiveness of polaprezinc for low-dose aspirin-induced small-bowel mucosal injuries as evaluated by capsule endoscopy: a pilot randomized controlled study. (2013). BMC Gastroenterol. 4(13), 108.
Cautions and Contraindications
Consult a health care practitioner if symptoms persist and/or worsen. If you have fever, vomiting, bloody diarrhea or severe abdominal pain, consult a health care practitioner prior to use. If symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond 3 days, discontinue use and consult a health care practitioner. Keep out of reach of children.
Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family. If you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment), do not use this product.
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